Tramadol generally marketed as ULTRAM is an opioid PAIN RELEIVING drug employed to cure MILD to harsh ache/pain. It is seen at times that Tramadol slows or completely stops the pain or ache. However, Tramadol is not a cure for the reason of pain. It just sidelines the pain for a period of time in case of chronic pain or pains which require a serious medical attention. When a person takes TRAMADOL as an instant-release oral formulation, the ache relief generally starts happening within about an hour. It has two diverse means. Primarily, it fixes to the µ-opioid receptor. Besides, it holds back the uptake of serotonin as well as epinephrine.