24-Oct-2016 11:07:36 am
Tramadol Side Effects: Something Not To Worry About Posted by Admin
Tramadol, available in the market to treat moderate to severely moderate pain, is one of the most potent analgesics. Still, like all other medicinal drugs, tramadol is also dangerous at times. Analgesics are not new to us. They are the traditional medicines that we all consume to cure different kinds of pains and aches. Tramadol and other opioids are prescribed for treating pains that occur as a result of an injury, surgery or fracture. Tramadol is the supreme opioid, that means it is better than all other opiate drugs in terms of effectiveness and has a lower addiction potential in comparison to opioids like morphine or codeine.
Tramadol is a potent drug and the danger of reactions or side effects is not unforeseen for patients. The action of Tramadol is exerted by affecting the opioid receptors. The mechanism of action of Tramadol is similar to other opioids like morphine. It inhibits the uptake of the neurochemicals in the brain which are, serotonin and norepinephrine. This mechanism is responsible for better therapeutic efficacy than morphine and codeine.
The most common adverse effects seen in tramadol are dry mouth, nausea, dizziness, vomiting and sedative effects. These side effects are tolerable and do not need any modification in the dose. However, dose adjustment can reduce the severity of these side effects.
Let's read about some uncommon side effects that are seldom observed with Tramadol:
Allergic Reactions: Tramadol may mildly or moderately cause allergic reactions in some individuals. The allergies may be as simple as normal itching or as serious as the formation of hives, difficulty in breathing, swelling of the mouth or entire face. In some rare cases, Tramadol may cause angioedema, that is a life- risking swelling of the vocal cords.
If you experience any such side effect, talk to your healthcare provider at once. Generally, allergic reactions because of Tramadol are caused in people who are genetically susceptible to opioid active chemicals. As a result of it, such people are likely to develop these allergic reactions to all other opiate medicines.
Central Nervous System Defects / CNS Defects: Although Tramadol primarily acts on the receptors in the brain, the risk of side effects on the Central Nervous System is surprisingly very low. CR Lee, in one of his research papers, suggested that regular intake of Tramadol for about six months forms a lower dependence and addiction potential as compared to other opiate drugs. However, when Tramadol is consumed for a prolonged period of time, the addiction potential is higher than other opioids. Its prolonged usage may cause vivid dreaming, nightmare, mood alteration, and hallucination in some people.
Respiratory Disorders: When Tramadol is administered through the infusion route, that is, as a part of the anesthesia protocol, it produces a very common complication, that is, respiratory depression. However, when Tramadol is administered through a controlled intravenous route during childbirth, the risk of respiratory depression is minimized. Any other respiratory side effect by Tramadol is rarely reported. Most of the mild or severe side effects can be reduced or avoided by adjusting and managing the dosage and route of drug administration. A much higher risk of side effects is associated with a rise in the level of active drug in the serum.
Gastric Side Effects: Tramadol has the potential of causing gastric problems because of its receptor-mediated effects on the body. Constipation is generally reported by many people after using Tramadol for a few weeks or months via oral administration. However, side effects like constipation, nausea, vomiting and other gastric problems are reduced with the prolonged use of Tramadol.
The risk of side effects by Tramadol is minimal. However, if any adverse effect is observed by any person, it can be controlled and treated with dose management and proper care.